USS Sumter may refer to:

• CSS Sumter a Confederate Navy vessel in the American Civil War
• USS Sumter (1862)Template:WP Ships USS instances, the former CSS General Sumter, a cottonclad ram captured in 1862
• USS Sumter (APA-52)Template:WP Ships USS instances (previously AP-97), an attack transport; formerly Iberville
• USS Sumter (LST-1181)Template:WP Ships USS instances, a tank landing ship

This article includes a list of ships with the same or similar names. If an internal link for a specific ship referred you to this page, you may wish to change the link to point directly to the intended ship article, if one exists.