Tropane alkaloids, also known as Belladonna alkaloids are a class of alkaloids and secondary metabolites that contain a tropane ring in their chemical structure. Tropane alkaloids occur naturally in many members of the plant family Solanaceae.

Important tropane alkaloids are:

Anticholinergics

Anticholinergic drugs and deliriants:

• Atropine, racemic hyoscyamine, from the deadly nightshade (Atropa belladonna)
• Hyoscyamine, the levo-isomer of atropine, from henbane (Hyoscamus niger) and mandrake (Mandragora officinalis)
• Scopolamine, from henbane and Datura species (Jimson weed)

Stimulants

Stimulants and cocaine-related alkaloids:

• Cocaine, from Erythroxylum coca
• Ecgonidine, and methylecgonidine, pyrolysis products of cocaine
• Ecgonine, a precursor and metabolite of cocaine
• Benzoylecgonine, a metabolite of cocaine
• Cocaethylene, a metabolite of cocaine
• Hydroxytropacocaine, from Erythroxylum coca
• Methylecgonine cinnamate, from Erythroxylum coca

Others

• Catuabines, found in the drug catuaba, from Erythroxylum vacciniifolium

Non-natural tropanes

• Phenyltropanes

See also

• Alkaloid
• Tropane