Trisomy 16 is a chromosomal abnormality in which there are three copies of chromosome 16 rather than two.1 It is the most common chromosomal cause of miscarriage during the first trimester of pregnancy.
It is not possible for a child to be born with an extra copy of this chromosome present in all cells (called Full Trisomy 16).2
It is possible to be born with the mosaic form.34
External links
References
- ^ Mary Kugler, R.N. (2005-08-20). "Chromosome 16 Disorders" (in English). About.com:Rare Diseases. About, Inc.. Retrieved on 2008-01-30.
- ^ Seller, MJ; Fear, C; Kumar, A; Mohammed, S (2004). "Trisomy 16 in a mid-trimester IVF foetus with multiple abnormalities". Clinical Dysmorphology (London: Lippincott Williams & Wilkins) 13 (3): 187–190. BL Shelfmark 3286.273700. ISSN 196772467. OCLC 196772467. PMID 15194958, http://www.clindysmorphol.com/pt/re/mcd/abstract.00019605-200407000-00013.htm.
- ^ Simensen, RJ; Colby, RS; Corning, KJ (2003). "A prenatal counseling conundrum: mosaic trisomy 16. A case study presenting cognitive functioning and adaptive behavior". Genetic Counselling (Geneva: Édition médicine et hygiène) 14 (3): 331–6. BL Shelfmark 4111.845000. ISSN 1015-8146. OCLC 210520912. PMID 14577678.
- ^ Langlois, S; Yong, P J; Yong, S L; Barrett, I; Kalousek, D K; Miny, P; Exeler, R; Morris, K; Robinson, W P (2006). "Postnatal follow-up of prenatally diagnosed trisomy 16 mosaicism". Prenatal Diagnosis (New York: John Wiley & Sons) 26 (6): 548–558. doi:10.1002/pd.1457. BL Shelfmark 6607.646000. ISSN 0197-3851. OCLC 108807898. PMID 16683298.
