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Mutant |
A mutant is an individual, organism, or new genetic character arising or resulting from an instance of mutation, which is a base-pair sequence change within the DNA of a gene or chromosome of an organism resulting in the creation of a new character or trait not found in the wild type. The natural occurrence of genetic mutations is integral to the process of evolution.
Although not all mutations have a noticeable phenotypic effect, the common usage of the word mutant is generally a pejorative term only used for noticeable mutations.1 The scientific usage is broader, referring to any organism differing from the wildtype.
Mutants should not be confused with organisms born of developmental abnormalities, which are caused by errors during morphogenesis. In a developmental abnormality, the DNA of the organism is unchanged and the abnormality cannot be passed on to progeny. Conjoined twins are the result of developmental abnormalities.
Chemicals that cause developmental abnormalities are called teratogens; these may also cause mutations, but their effect on development is not related to mutations. Chemicals that induce mutations are called mutagens. Most mutagens are also considered to be carcinogens.