Lymphokine-activated_killer

Lymphokine-activated killer cell

In cell biology, a lymphokine-activated killer cell (also known as a LAK cell) is a white blood cell that has been stimulated to kill tumour cells.¹ If lymphocytes are cultured in the presence of Interleukin 2, it results in the development of effector cells which are cytotoxic to tumour cells.²

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v • d • e Blood

General	Plasma – Hematopoietic stem cells

Lymphoid – WBC	T cells: Cytotoxic CD8⁺, Helper CD4⁺/Regulatory, γδ, Natural Killer T cell B cells: Plasma, Memory Natural killer cells (Lymphokine-activated killer cell) Null cell

Myeloid – WBC	Monocytes/Macrophages (Histiocytes, Kupffer cells, Dust cell, Microglia, Osteoclasts, Epithelioid cells, Langhans giant cells, Foreign-body giant cell) Granulocytes (Neutrophil, Eosinophil, Basophil) – Mast cell precursors Dendritic cells (Langerhans cells, Follicular dendritic cells) Megakaryoblast – Megakaryocyte – Platelets

Myeloid – RBC	Reticulocyte – Normoblast